(PhysOrg.com) -- For the first time, Yale researchers have identified common genetic variants that predispose lean individuals to nonalcoholic fatty liver disease (NAFLD) and insulin resistance. NAFLD is now the most common chronic liver disease in the U.S. and insulin resistance is the major factor that leads to type 2 diabetes. Their study also explains the mechanism by which individuals develop these conditions, despite maintaining normal body weight. The research appears in the March 25, 2010 issue of the New England Journal of Medicine.
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